Detalhe da pesquisa
1.
Analysis of Genetically Diverse Macrophages Reveals Local and Domain-wide Mechanisms that Control Transcription Factor Binding and Function.
Cell
; 173(7): 1796-1809.e17, 2018 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779944
2.
Transcriptomic and epigenetic mechanisms underlying myeloid diversity in the lung.
Nat Immunol
; 21(2): 221-231, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31959980
3.
Environment drives selection and function of enhancers controlling tissue-specific macrophage identities.
Cell
; 159(6): 1327-40, 2014 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-25480297
4.
The selection and function of cell type-specific enhancers.
Nat Rev Mol Cell Biol
; 16(3): 144-54, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25650801
5.
TNFα increases the degradation of pyruvate dehydrogenase kinase 4 by the Lon protease to support proinflammatory genes.
Proc Natl Acad Sci U S A
; 120(38): e2218150120, 2023 09 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37695914
6.
Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations.
Genome Res
; 32(3): 409-424, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35193936
7.
Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function.
Immunity
; 45(5): 975-987, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27814941
8.
Unraveling the Role of Sex in Endothelial Cell Dysfunction: Evidence From Lineage Tracing Mice and Cultured Cells.
Arterioscler Thromb Vasc Biol
; 44(1): 238-253, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38031841
9.
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro.
Arterioscler Thromb Vasc Biol
; 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38602103
10.
Integrative analysis of liver-specific non-coding regulatory SNPs associated with the risk of coronary artery disease.
Am J Hum Genet
; 108(3): 411-430, 2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33626337
11.
SREBP2 regulates the endothelial response to cytokines via direct transcriptional activation of KLF6.
J Lipid Res
; 64(8): 100411, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37437844
12.
Systems Genetics in Human Endothelial Cells Identifies Non-coding Variants Modifying Enhancers, Expression, and Complex Disease Traits.
Am J Hum Genet
; 106(6): 748-763, 2020 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32442411
13.
Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.
Circ Res
; 129(2): 240-258, 2021 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34024118
14.
CC16 Binding to α4ß1 Integrin Protects against Mycoplasma pneumoniae Infection.
Am J Respir Crit Care Med
; 203(11): 1410-1418, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33326355
15.
Genome-wide analysis identifies novel susceptibility loci for myocardial infarction.
Eur Heart J
; 42(9): 919-933, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33532862
16.
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription.
Mol Cell
; 51(3): 310-25, 2013 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-23932714
17.
Genetic variant at coronary artery disease and ischemic stroke locus 1p32.2 regulates endothelial responses to hemodynamics.
Proc Natl Acad Sci U S A
; 115(48): E11349-E11358, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429326
18.
MMARGE: Motif Mutation Analysis for Regulatory Genomic Elements.
Nucleic Acids Res
; 46(14): 7006-7021, 2018 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-29893919
19.
An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner.
J Lipid Res
; 60(4): 869-879, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30598475
20.
Exploiting genomics and natural genetic variation to decode macrophage enhancers.
Trends Immunol
; 36(9): 507-18, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26298065